Lysosomal accumulation of intravenously administered hyaluronidase.

Abstract

Rat tail tendon collagen fibrils disaggregated in the mild experimental conditions to sub-fibrillar structures. The smallest, most frequent (protofibrils) were of fairly constant thickness, 12-15 nm. They often arose from larger subfibrils ( > 25 nm) that were nevertheless much smaller than the parent fibril. The protofibrils retained a faint banding… (More)

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