Lysophospholipid activation of G protein-coupled receptors.

@article{Mutoh2008LysophospholipidAO,
  title={Lysophospholipid activation of G protein-coupled receptors.},
  author={Tetsuji Mutoh and Jerold Chun},
  journal={Sub-cellular biochemistry},
  year={2008},
  volume={49},
  pages={
          269-97
        }
}
One of the major lipid biology discoveries in last decade was the broad range of physiological activities of lysophospholipids that have been attributed to the actions of lysophospholipid receptors. The most well characterized lysophospholipids are lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Documented cellular effects of these lipid mediators include growth-factor-like effects on cells, such as proliferation, survival, migration, adhesion, and differentiation. The mechanisms… CONTINUE READING
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