Corpus ID: 91813037

Lysophosphatidylcholine Inhibits Receptor-Mediated Ca2+ Mobilization in Intact Endothelial Cells of Rabbit Aorta

@inproceedings{YoichiMiwa1997LysophosphatidylcholineIR,
  title={Lysophosphatidylcholine Inhibits Receptor-Mediated Ca2+ Mobilization in Intact Endothelial Cells of Rabbit Aorta},
  author={YoichiMiwa and Ken-ichiHirata and SeinosukeKawashima and HozukaAkita and MitsuhiroYokoyama},
  year={1997}
}
Abstract We have previously reported that lysophosphatidylcholine (LPC), which accumulates in oxidized LDL and atherosclerotic arteries, inhibits endothelium-dependent relaxation and modulates Ca2+ regulation in cultured bovine aortic endothelial cells. To test the effect of LPC on endothelium-dependent relaxation and endothelial Ca2+ regulation in intact vessels, we simultaneously measured both isometric tension and endothelial cytosolic free Ca2+ concentration ([Ca2+]i), using fura 2, in… Expand
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