Lysophosphatidic acid signalling in development.

  title={Lysophosphatidic acid signalling in development.},
  author={Xiaoyan Sheng and Yun C Yung and Allison Chen and Jerold Chun},
  volume={142 8},
Lysophosphatidic acid (LPA) is a bioactive phospholipid that is present in all tissues examined to date. LPA signals extracellularly via cognate G protein-coupled receptors to mediate cellular processes such as survival, proliferation, differentiation, migration, adhesion and morphology. These LPA-influenced processes impact many aspects of organismal development. In particular, LPA signalling has been shown to affect fertility and reproduction, formation of the nervous system, and development… CONTINUE READING
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