Lysophosphatidic acid enhances contractility of isolated airway smooth muscle.

@article{Toews1997LysophosphatidicAE,
  title={Lysophosphatidic acid enhances contractility of isolated airway smooth muscle.},
  author={Myron L. Toews and Elena E. Ustinova and Harold D. Schultz},
  journal={Journal of applied physiology},
  year={1997},
  volume={83 4},
  pages={1216-22}
}
The effects of the simple phospholipid mediator lysophosphatidic acid (LPA) on the contractile responsiveness of isolated tracheal rings from rabbits and cats were assessed. In both species, LPA increased the contractile response to the muscarinic agonist methacholine, but LPA did not induce contraction on its own. Conversely, LPA decreased the relaxation… CONTINUE READING