Lysogeny with Shiga Toxin 2-Encoding Bacteriophages Represses Type III Secretion in Enterohemorrhagic Escherichia coli

@inproceedings{Xu2012LysogenyWS,
  title={Lysogeny with Shiga Toxin 2-Encoding Bacteriophages Represses Type III Secretion in Enterohemorrhagic Escherichia coli},
  author={Xuefang Xu and Sean P. McAteer and Jai J Tree and Darren J Shaw and Eliza B. K. Wolfson and Scott A. Beatson and Andrew J Roe and Lesley J. Allison and Margo E. Chase-Topping and Arvind Mahajan and Rosangela Tozzoli and Mark E. J. Woolhouse and Stefano Morabito and David L. Gally},
  booktitle={PLoS pathogens},
  year={2012}
}
Lytic or lysogenic infections by bacteriophages drive the evolution of enteric bacteria. Enterohemorrhagic Escherichia coli (EHEC) have recently emerged as a significant zoonotic infection of humans with the main serotypes carried by ruminants. Typical EHEC strains are defined by the expression of a type III secretion (T3S) system, the production of Shiga toxins (Stx) and association with specific clinical symptoms. The genes for Stx are present on lambdoid bacteriophages integrated into the E… CONTINUE READING
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