Lysinoalanine: absence of mutagenic response in the Salmonella/mammalian-microsome mutagenicity assay.

@article{Pintauro1985LysinoalanineAO,
  title={Lysinoalanine: absence of mutagenic response in the Salmonella/mammalian-microsome mutagenicity assay.},
  author={Stephen J. Pintauro and Guy Philippossian and Patrick Finot and Thomas Chadwick Lee},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={1985},
  volume={23 8},
  pages={
          763-5
        }
}
Lysinoalanine (N epsilon-(DL-2-amino-2-carboxyethyl)-L-lysine) was tested for mutagenicity in the Ames Salmonella/mammalian-microsome mutagenicity assay. No mutagenic response was detected at doses up to 5 mg/plate when samples were pre-incubated without S-9 mix, nor when they were pre-incubated with S-9 mix prepared from Aroclor 1254-induced rat liver or kidney. The results indicate that the stereoisomers of lysinoalanine likely to be present in the greatest proportions in processed foods are… CONTINUE READING
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