Lysine transport across rat jejunum: distribution between the transcellular and the paracellular routes.

@article{Munck1979LysineTA,
  title={Lysine transport across rat jejunum: distribution between the transcellular and the paracellular routes.},
  author={Bjarne Gyldenl\ove Munck and S\oren N. Rasmussen},
  journal={The Journal of physiology},
  year={1979},
  volume={291},
  pages={291-303}
}
Transport of lysine across the rat jejunum has been studied measuring transmural fluxes, Jms and Jsm, under short-circuit conditions, influx across the brush-border membrane, Jmc, under open-circuit and voltage-clamp conditions, and steady-state uptake by the isolated mucosa. 1. Jlysmc can be described as the sum of a saturable process with a Kt of 3 mM and a Jmax of 2.25 micromole/cm2.hr and a diffusional component corresponding to a lysine permeability of 0.014 cm/hr. Also Jlysms is well… CONTINUE READING
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