Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function.

@article{Voelkel2013LysineMS,
  title={Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function.},
  author={Tobias Voelkel and Christian Andresen and A. U. Unger and Steffen Just and Wolfgang Rottbauer and Wolfgang A Linke},
  journal={Biochimica et biophysica acta},
  year={2013},
  volume={1833 4},
  pages={812-22}
}
Protein lysine methylation controls gene expression and repair of deoxyribonucleic acid in the nucleus but also occurs in the cytoplasm, where the role of this posttranslational modification is less understood. Members of the Smyd protein family of lysine methyltransferases are particularly abundant in the cytoplasm, with Smyd1 and Smyd2 being most highly expressed in the heart and in skeletal muscles. Smyd1 is a crucial myogenic regulator with histone methyltransferase activity but also… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis.

Biochimica et biophysica acta • 2014
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…