Corpus ID: 25480525

Lysine acetylsalicylate ameliorates lung injury in rats acutely exposed to paraquat.

  title={Lysine acetylsalicylate ameliorates lung injury in rats acutely exposed to paraquat.},
  author={W. Huang and Jie-zan Wang and Yuan-qiang Lu and Ya-Min Di and Jiu-kun Jiang and Q. Zhang},
  journal={Chinese medical journal},
  volume={124 16},
BACKGROUND Paraquat (PQ), an effective and widely used herbicide, has been proven to be safe when appropriately applied to eliminate weeds. However, PQ poisoning is an extremely frustrating clinical condition with a high mortality and with a lack of effective treatments in humans. PQ mainly accumulates in the lung, and the main molecular mechanism of PQ toxicity is based on redox cycling and intracellular oxidative stress generation. The aim of this study was to evaluate whether lysine… Expand
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