Lysine Acetylation: Elucidating the Components of an Emerging Global Signaling Pathway in Trypanosomes

@inproceedings{Alonso2012LysineAE,
  title={Lysine Acetylation: Elucidating the Components of an Emerging Global Signaling Pathway in Trypanosomes},
  author={Victoria Lucia Alonso and Esteban Carlos Serra},
  booktitle={Journal of biomedicine & biotechnology},
  year={2012}
}
In the past ten years the number of acetylated proteins reported in literature grew exponentially. Several authors have proposed that acetylation might be a key component in most eukaryotic signaling pathways, as important as phosphorylation. The enzymes involved in this process are starting to emerge; acetyltransferases and deacetylases are found inside and outside the nuclear compartment and have different regulatory functions. In trypanosomatids several of these enzymes have been described… CONTINUE READING