LysK, the enzyme lysing Staphylococcus aureus cells: specific kinetic features and approaches towards stabilization.

@article{Filatova2010LysKTE,
  title={LysK, the enzyme lysing Staphylococcus aureus cells: specific kinetic features and approaches towards stabilization.},
  author={Lyubov Yu Filatova and Stephen C. Becker and David M. Donovan and Alexander K. Gladilin and Natalia L Klyachko},
  journal={Biochimie},
  year={2010},
  volume={92 5},
  pages={507-13}
}
LysK, the enzyme lysing cells of Staphylococcus aureus, can be considered as perspective antimicrobial agent. Knowledge of LysK properties and behavior would allow optimizing conditions of its storage as well as formulating strategy towards its stabilization. Reaction of LysK with substrate (suspension of autoclaved Staphylococcus aureus cells) has been found to be adequately described by the two-stage Michaelis-Menten kinetic scheme. Ionization of the enzyme and enzyme-substrate complex is… CONTINUE READING

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