Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation

Abstract

Hypersecretion of mucus is an important component of airway remodeling and contributes to the mucus plugs and airflow obstruction associated with severe asthma phenotypes. Lyn has been shown to down-regulate allergen-induced airway inflammation. However, the role of Lyn in mucin gene expression remains unresolved. In this study, we first demonstrate that… (More)
DOI: 10.1038/srep42675

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Cite this paper

@inproceedings{Wang2017LynRM, title={Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation}, author={Xiaoyun Wang and Yin Li and Deyu Luo and Xing Wang and Yun Zhang and Zhigang Liu and Nan-shan Zhong and Min Wu and Guoping Li}, booktitle={Scientific reports}, year={2017} }