Lyn- and ERK-mediated vs. Ca2+ -mediated neutrophil O responses with thermal injury.

@article{Fazal2002LynAE,
  title={Lyn- and ERK-mediated vs. Ca2+ -mediated neutrophil O responses with thermal injury.},
  author={Nadeem Fazal and Walid M. Al-Ghoul and Megan J Schmidt and Mashkoor A. Choudhry and M. M. Alamgir Sayeed},
  journal={American journal of physiology. Cell physiology},
  year={2002},
  volume={283 5},
  pages={C1469-79}
}
We evaluated the dependency of neutrophil O production on PTK-Lyn and MAPK-ERK1/2 in rats after thermal injury. Activation of PTK-Lyn was assessed by immunoprecipitation. Phosphorylation of ERK1/2 was assessed by Western blot analysis. O production was measured by isoluminol-enhanced luminometry. Imaging technique was employed to measure neutrophil [Ca2+](i… CONTINUE READING