Lymphotoxin and LIGHT signaling pathways and target genes.

@article{Schneider2004LymphotoxinAL,
  title={Lymphotoxin and LIGHT signaling pathways and target genes.},
  author={Kirsten Schneider and Karen G. Potter and Carl F Ware},
  journal={Immunological reviews},
  year={2004},
  volume={202},
  pages={
          49-66
        }
}
Lymphotoxins (LT alpha and LT beta), LIGHT [homologous to LT, inducible expression, competes with herpes simplex virus (HSV) glycoprotein D for HSV entry mediator (HVEM), a receptor expressed on T lymphocytes], tumor necrosis factor (TNF), and their specific receptors LT beta R, HVEM, and TNF receptor 1 (TNFR1) and TNFR2, form the immediate family of the larger TNF superfamily. These cytokines establish a critical communication system required for the development of secondary lymphoid tissues… CONTINUE READING

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