Lymphoplasmacytic infiltration of multiple organs with immunoreactivity for IgG4: IgG4-related systemic disease.

@article{Saeki2006LymphoplasmacyticIO,
  title={Lymphoplasmacytic infiltration of multiple organs with immunoreactivity for IgG4: IgG4-related systemic disease.},
  author={Takako Saeki and Akihiko Saito and Tohru Hiura and Hajime Yamazaki and Iwao Emura and Mitsuhiro Ueno and Syoji Miyamura and Fumitake Gejyo},
  journal={Internal medicine},
  year={2006},
  volume={45 3},
  pages={163-7}
}
We report three elderly men with high serum IgG4 concentrations and multiple lymphoplasmacytic inflammation of the salivary glands, lymph nodes, pancreas, and renal interstitium. The infiltrating plasma cells had strong immunoreactivity for IgG4, even in patients without pancreatic lesions. These cases show that IgG4 is associated not only with autoimmune… CONTINUE READING