Lymphoma in Severe Combined Immunodeficient Mice Interleukin 4 Retards Dissemination of a Human B-Cell

We have examined the antitumor activity of murine interleukin 4 (IL-4) on development of a human B-cell lymphoma (Daudi) in severe combined immunodeficient (SCID) mice. The progression of Daudi cells in SCID mice was followed by histolÃ3gica! staining and by flow cytometric analysis of CD20+ cells in spleen, liver, bone marrow, and kidneys. By day 35, ( '1… CONTINUE READING