Lymphoepithelioma-like Hepatocellular Carcinoma: An Uncommon Variant of Hepatocellular Carcinoma With Favorable Outcome
@article{Chan2015LymphoepitheliomalikeHC, title={Lymphoepithelioma-like Hepatocellular Carcinoma: An Uncommon Variant of Hepatocellular Carcinoma With Favorable Outcome}, author={Anthony Wing-Hung Chan and Joanna Hung-Man Tong and Yi-lian Pan and Stephen Lam Chan and Grace Lai‐Hung Wong and Vincent Wai‐Sun Wong and Paul B. S. Lai and Ka Fai To}, journal={The American Journal of Surgical Pathology}, year={2015}, volume={39}, pages={304–312} }
Lymphoepithelioma-like hepatocellular carcinoma (LEL-HCC) is an uncommon variant of HCC with only 22 cases reported in the literature. To better determine the incidence, clinicopathologic features, prognostic significance, and molecular pathogenesis of LEL-HCC, we presented the largest series of LEL-HCC from a 9-year retrospective cohort of patients with HCC undergoing surgical resection. LEL-HCC was identified in 20 patients (4.9%). Compared with patients having HCC without significant tumor…
52 Citations
Lymphoepithelioma-like hepatocellular carcinoma
- Medicine, BiologyMedicine
- 2017
This case was the youngest patient of all the reported cases, and the third case who was infected with both hepatitis B virus (HBV) and hepatitis C virus (HCV).
Lymphoepithelioma-like hepatocellular carcinoma: Case report and review of the literature.
- MedicineWorld journal of gastroenterology
- 2015
The clinicopathological features of the case are reported, along with a review of the few cases present in the literature, to report on the synchronous occurrence of HCC and GIST.
Synchronous hepatocellular carcinoma and lymphoepithelioma-like carcinoma arising from 2 different sites of the liver
- MedicineMedicine
- 2018
This is an interesting case providing circumstantial evidence of simultaneous development of HCC and LEL-HCC in distinct nodules of the liver with a background of chronic hepatitis B virus infection.
Lymphoepithelioma-like Hepatocellular Carcinoma: a Case Report and Review of Literature
- MedicineJournal of Gastrointestinal Cancer
- 2021
A case of hepatic lymphoepithelioma-like carcinoma-hepatocellular carcinoma subtype (LEL-HCC), a rare variant of HCC with a relatively better prognosis, in a 41-year-old man with chronic hepatitis C virus infection is reported.
Metastatic lymphoepithelioma-like hepatocellular carcinoma: a potential diagnostic pitfall and demonstration of PD-L1 expression.
- MedicineAnnals of hepatology
- 2017
A 73-year-old female with chronic hepatitis B who developed metastatic lesions 5 years after underwent resection for LEL-HCC showed a spectrum of morphologic findings, which could be mistaken for other entities such as lymphoma, particularly in lesions with single-cell infiltrate pattern and abundant tumor-infiltrating lymphocytes.
Lymphoepithelioma-Like Cholangiocarcinoma Associated With HCV: A Case Report and a Review of the Literature
- Medicine
- 2016
A rare cases of HCV-associated LEL-CC that coexisted with other malignancy and that was associated with survival for more than 3 years after surgery is described, suggesting that surgical resection may be the recommended therapeutic option for Lel-CC.
Lymphoepithelioma-Like Hepatocellular Carcinoma: Report of Three Cases and Review of Literature
- Medicine, Biology
- 2015
Three cases of lymphoepithelioma-like hepatocellular carcinoma (HCC) in one female and two male patients are reported, composed of a population of malignant cells with focal to diffuse positivity for HepPar-1, as well as a prominent lymphoplasmacytic infiltrate intimately associated with themalignant cells.
Lymphoepithelioma-like hepatocellular carcinoma: a case report with emphasis on the cytological features.
- MedicineInternational journal of clinical and experimental pathology
- 2017
The cytological features of the present case represent both lymphoepithelioma-like carcinoma and conventional HCC, and the prognosis of LEL-HCC may be favorable.
Lymphoepithelioma-like hepatic carcinoma: A report of 3 cases and review of the literature
- Medicine
- 2020
It is suggested that even the locally advanced patients of LELC with postoperative recurrence and preoperative lymph node metastasis should be actively treated and intervened for a longer survival period.
Lymphoepithelioma-Like Carcinoma in Liver.
- Medicine, BiologyThe American journal of pathology
- 2017
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