Lymphoepithelial carcinoma of the larynx and hypopharynx: study of eight cases with relationship to Epstein-Barr virus and p53 gene alterations, and review of the literature.

@article{Macmillan1996LymphoepithelialCO,
  title={Lymphoepithelial carcinoma of the larynx and hypopharynx: study of eight cases with relationship to Epstein-Barr virus and p53 gene alterations, and review of the literature.},
  author={Christine Macmillan and Silloo B. Kapadia and Sydney D. Finkelstein and Michael Andrew Nalesnik and Leon Barnes},
  journal={Human pathology},
  year={1996},
  volume={27 11},
  pages={1172-9}
}
Eight cases of lymphoepithelial carcinoma (LEC) of the larynx and hypopharynx were evaluated for clinicopathologic features, and the presence of the Epstein-Barr virus (EBV) and p53 alterations. The seven men and one woman, all of non-Asian descent, averaged 64 years of age. Eighty-eight percent had histologically confirmed cervical lymph node metastasis at diagnosis. None had systemic disease. Seven of eight patients available for follow-up (mean, 17.7 months) were alive and free of disease… CONTINUE READING

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