Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl

@article{Bettendorf1999LymphocyticHW,
  title={Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl},
  author={Markus Bettendorf and Marita Fehn and Juergen Grulich-Henn and Barbara Selle and Kassa Darge and Dieter K. L{\"u}decke and Udo E Heinrich and Wolfgang Saeger},
  journal={European Journal of Pediatrics},
  year={1999},
  volume={158},
  pages={288-292}
}
We report the clinical course of a prepubertal girl with central diabetes insipidus (DI) and consequent panhypopituitarism evolving over a period of 10 years due to lymphocytic hypophysitis and subsequent germinoma. Two years after the diagnosis of central DI was established, MRI revealed a thickened pituitary stalk. Later pituitary enlargement and… CONTINUE READING