Lymphocytic choriomeningitis virus-induced mortality in mice is triggered by edema and brain herniation.

Abstract

Although much is known about lymphocytic choriomeningitis virus (LCMV) infection and the subsequent immune response in its natural murine host, some crucial aspects of LCMV-mediated pathogenesis remain undefined, including the underlying basis of the characteristic central nervous system disease that occurs following intracerebral (i.c.) challenge. We show… (More)
DOI: 10.1128/JVI.00727-09

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