Lymphocytes activated by the Epstein-Barr virus to produce immunoglobulin do not express CD23 or become immortalized.

@article{Azim1988LymphocytesAB,
  title={Lymphocytes activated by the Epstein-Barr virus to produce immunoglobulin do not express CD23 or become immortalized.},
  author={T Azim and Dorothy H. Crawford},
  journal={International journal of cancer},
  year={1988},
  volume={42 1},
  pages={23-8}
}
Epstein-Barr virus causes polyclonal activation and immortalization of a small percentage of peripheral blood B lymphocytes after in vitro infection. However, the susceptible B lymphocytes have not been identified. We have used the B lymphocyte activation antigen, CD23, as a marker for separating immortalized and non-immortalized Epstein-Barr virus-infected B lymphocytes and have identified the polyclonally-activated cells, using double staining for cytoplasmic immunoglobulin and viral antigens… CONTINUE READING