Lymphocyte transformation and changes in leukocyte count: effects of anesthesia and operation.

@article{Cullen1975LymphocyteTA,
  title={Lymphocyte transformation and changes in leukocyte count: effects of anesthesia and operation.},
  author={Bruce F. Cullen and Gerald van Belle},
  journal={Anesthesiology},
  year={1975},
  volume={43 5},
  pages={563-9}
}
The transformation of lymphocytes in response to phytohemagglutinin stimulation was investigated in 77 patients undergoind anesthesia with and without coincident surgical operation. A depression of lymphocyte transformation apparent immediately following major operations was related primarily to the extent of tissue trauma and not to the anesthetic agent or technique. No depression of lymphocyte transformation followed anesthesia for treatment of pain or for minor operations. The total… CONTINUE READING