Lymphocyte subsets associated with major depression and dysthymia: modification by antidepressant treatment.

@article{Ravindran1995LymphocyteSA,
  title={Lymphocyte subsets associated with major depression and dysthymia: modification by antidepressant treatment.},
  author={Arun V Ravindran and J. G. Griffiths and Zul Merali and Hymie Anisman},
  journal={Psychosomatic medicine},
  year={1995},
  volume={57 6},
  pages={555-63}
}
Major depression and dysthymia (chronic, low grade depression) were associated with an increase in the number of CD16/56 (natural killer; NK) cells in blood, whereas other lymphocyte subsets (CD3, CD4, CD8, CD19, and the CD4/CD8 ratio) did not differ from control subjects. After treatment with a specific serotonin reuptake inhibitor, the symptoms of depression were alleviated in both the major depressive and dysthymic patients. Likewise, NK cell numbers declined to control values in these… CONTINUE READING

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