Lymphocyte recovery predicts outcomes in cord blood and T cell-depleted haploidentical stem cell transplantation.

@article{Ciurea2011LymphocyteRP,
  title={Lymphocyte recovery predicts outcomes in cord blood and T cell-depleted haploidentical stem cell transplantation.},
  author={Stefan O Ciurea and Victor Eduardo Mulanovich and Ying Jiang and Roland Bassett and Gabriela Rond{\'o}n and John Mcmannis and Marcos de Lima and Elizabeth J Shpall and Richard E. Champlin},
  journal={Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation},
  year={2011},
  volume={17 8},
  pages={1169-75}
}
Alternative donor stem cell transplantation from cord blood or haploidentical peripheral blood donors is increasingly being used for patients who lack a matched related or unrelated donor. A higher nonrelapse mortality (NRM) rate has been noted with these 2 types of transplants, primarily because of infectious complications. Here, we hypothesized that the time to lymphocyte recovery (absolute lymphocyte count [ALC] of ≥1000/μL for the first 3 consecutive days) after transplant correlates with… CONTINUE READING
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