Lymphocyte numbers and function in relation to periodontitis and smoking.

  title={Lymphocyte numbers and function in relation to periodontitis and smoking.},
  author={Bruno G. Loos and Marijke Th. L. Roos and Peter Th A Schellekens and Ubele Van der Velden and Frank A Miedema},
  journal={Journal of periodontology},
  volume={75 4},
BACKGROUND T and B lymphocytes play important roles in periodontitis. Smoking is considered a risk factor for periodontitis and may exert its negative effects through leukocytes. Taking smoking into consideration, the aim of this study was to analyze numbers of circulating T (CD3+) cells and their CD4+ and CD8+ subpopulations, B (CD19+) cells, and T-cell proliferative capacity in periodontitis. METHODS Lymphocyte immunophenotyping for T cells, their CD4+ and CD8+ subsets, and B cells was… CONTINUE READING

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