Lymphocyte function in major depression.

  title={Lymphocyte function in major depression.},
  author={Lori L. Altshuler and Susan Plaeger-Marshall and Steven H. Richeimer and Marion Daniels and Lewis Baxter},
  journal={Acta psychiatrica Scandinavica},
  volume={80 2},
Immunologic function as measured by lymphocyte response to phytohemagglutinin (PHA) mitogen was evaluated in 8 psychiatric inpatients. All were less than 45 years of age and had a DSM-III diagnosis of major depression. When patient's immunologic responses were compared with healthy age- and sex-matched controls, a significant increase in PHA mitogen stimulation was observed in the depressed group. Further, a significantly greater variance in PHA response was observed in the patients compared… CONTINUE READING

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