Lymphocyte function during hepatic ischemia/reperfusion injury.

  title={Lymphocyte function during hepatic ischemia/reperfusion injury.},
  author={Charles C Caldwell and Johannes Tschoep and Alex B. Lentsch},
  journal={Journal of leukocyte biology},
  volume={82 3},
The liver is the primary organ affected by ischemia/reperfusion (I/R) injury after shock, surgical resection, or transplantation. The actions of myeloid leukocytes have been well studied and are thought to be the primary cells responsible for propagating the injury response. However, there is an emerging view that T lymphocytes can also regulate liver I/R-induced inflammation. Resident lymphocytes found within the liver include conventional alphabeta TCR cells as well as unconventional NK and… CONTINUE READING


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