Lymphocyte effector functions

  title={Lymphocyte effector functions},
  author={Michel Neidhart and Nik Hauser and Mats Paulsson and Paul E Dicesare and Ferenc Pataki and Beat Michel and Blaise Corth{\'e}sy},
Eukaryotic cells that are transformed by oncogenic viruses undergo dramatic changes in their phenotype. It is likely that these changes are caused by the specific loss of proteins from the cell membrane and the cytoskeleton. To investigate these alterations at the molecular level, we prepared a subtracted cDNA library with mRNA from normal human fibroblasts and from their SV40 transformed counterparts. About one third of the clones obtained in this way showed the expected down-regulation on a… CONTINUE READING