Lymphocyte development in fish and amphibians

  title={Lymphocyte development in fish and amphibians},
  author={J. Hansen and A. Zapata},
  journal={Immunological Reviews},
  • J. Hansen, A. Zapata
  • Published 1998
  • Biology, Medicine
  • Immunological Reviews
  • Summary: Recently, molecular markers such as recombination activating genes (RAG), terminal deoxynucleotidyl transferase (TdT), stem cell leukemia hematopoletic transcription factor (SCL), Ikaros and gata‐binding protein (Gata) ‐family members have been isolated and characterized from key lower vertebrates, adding to our growing knowledge of lymphopolesis in ectotherms. In all gnathostomes there appear to be two main embryonic locations derived from the early mesoderm, both intra‐ and… CONTINUE READING
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