Lymphocyte/macrophage interactions: biomaterial surface-dependent cytokine, chemokine, and matrix protein production.

@article{Chang2008LymphocytemacrophageIB,
  title={Lymphocyte/macrophage interactions: biomaterial surface-dependent cytokine, chemokine, and matrix protein production.},
  author={David T. Chang and Jacqueline A Jones and Howard Meyerson and Erica Colton and Il Keun Kwon and Takehisa Matsuda and James M Anderson},
  journal={Journal of biomedical materials research. Part A},
  year={2008},
  volume={87 3},
  pages={
          676-87
        }
}
The role of lymphocytes in the biological response to synthetic polymers is poorly understood despite the transient appearance of lymphocytes at the biomaterial implant site. To investigate cytokines, chemokines, and extracellular matrix (ECM) proteins produced by lymphocytes and macrophages in response to biomaterial surfaces, human peripheral blood monocytes and lymphocytes were co-cultured on polyethylene terephthalate (PET)-based material surfaces displaying distinct hydrophobic… CONTINUE READING
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