Lymphangiogenesis in vitro: formation of lymphatic capillary-like channels from confluent monolayers of lymphatic endothelial cells.

@article{Leak1994LymphangiogenesisIV,
  title={Lymphangiogenesis in vitro: formation of lymphatic capillary-like channels from confluent monolayers of lymphatic endothelial cells.},
  author={Lee V. Leak and Mortyn Jones},
  journal={In vitro cellular & developmental biology. Animal},
  year={1994},
  volume={30A 8},
  pages={
          512-8
        }
}
Lymphatic endothelial cells grown long term in culture form lymphatic capillary-like tubes. Examination by light and transmission electron microscopy showed that these structures were closed loops composed of one to several cells connected by intercellular junction to form a luminal space. This first demonstration of lymphangiogenesis in confluent monolayer cultures of lymphatic endothelial cells (a) showed that collagen type I accelerated lymphatic capillary tube formation, whereas fibronectin… CONTINUE READING
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