Lymph node metastases: safety and effectiveness of MR imaging with ultrasmall superparamagnetic iron oxide particles--initial clinical experience.

@article{Bellin1998LymphNM,
  title={Lymph node metastases: safety and effectiveness of MR imaging with ultrasmall superparamagnetic iron oxide particles--initial clinical experience.},
  author={M. F. Bellin and Catherine Roy and Karen Kinkel and Denis Thoumas and Souhil Zaim and Daniel Vanel and C M Tuchmann and Francois Richard and Didier Jacqmin and Annick Delcourt and Emmanuel Challier and Thierry Lebr{\'e}t and Philippe Cluzel},
  journal={Radiology},
  year={1998},
  volume={207 3},
  pages={799-808}
}
PURPOSE To evaluate the clinical and biologic safety of ultrasmall superparamagnetic iron oxide particles (AMI-227) as a contrast agent for magnetic resonance (MR) lymphography and to assess their efficacy for the differentiation of metastatic and benign nodes in patients with urologic and pelvic cancer. MATERIALS AND METHODS Thirty adults suspected of having lymph node metastases underwent MR imaging before and 22-26 hours after intravenous infusion of AMI-227 (1.7 mg Fe/kg). Sixty… CONTINUE READING

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