Lymph node fibroblastic reticular cells in health and disease

@article{Fletcher2015LymphNF,
  title={Lymph node fibroblastic reticular cells in health and disease},
  author={Anne L Fletcher and Sophie E. Acton and Konstantin Knoblich},
  journal={Nature Reviews Immunology},
  year={2015},
  volume={15},
  pages={350-361}
}
Over the past decade, a series of discoveries relating to fibroblastic reticular cells (FRCs) — immunologically specialized myofibroblasts found in lymphoid tissue — has promoted these cells from benign bystanders to major players in the immune response. In this Review, we focus on recent advances regarding the immunobiology of lymph node-derived FRCs, presenting an updated view of crucial checkpoints during their development and their dynamic control of lymph node expansion and contraction… CONTINUE READING

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