Lymph node T-cells do not optimally transfer diabetes in NOD mice.

@article{Lepault1993LymphNT,
  title={Lymph node T-cells do not optimally transfer diabetes in NOD mice.},
  author={Françoise Lepault and Christelle Faveeuw and Jian Jian Luan and M C Gagnerault},
  journal={Diabetes},
  year={1993},
  volume={42 12},
  pages={1823-8}
}
The nonobese diabetic mouse in a model of spontaneous development of autoimmune type I diabetes. The disease can be induced in young, irradiated recipients by injecting splenic T-cells from diabetic donors. The adoptive transfer of diabetes requires the presence of both CD4+ and CD8+ splenic T-cell subsets. To test whether diabetogenic cells distribute in… CONTINUE READING