Lymph Node Cellular Dynamics in Cancer and HIV: What Can We Learn for the Follicular CD4 (Tfh) Cells?

@inproceedings{Poultsidi2018LymphNC,
  title={Lymph Node Cellular Dynamics in Cancer and HIV: What Can We Learn for the Follicular CD4 (Tfh) Cells?},
  author={Antigoni A Poultsidi and Yiannis Dimopoulos and Ting-Fang He and Triantafyllos Chavakis and Emmanouil Saloustros and Peter Poon-Hang Lee and Constantinos Petrovas},
  booktitle={Front. Immunol.},
  year={2018}
}
Lymph nodes (LNs) are central in the generation of adaptive immune responses. Follicular helper CD4 T (Tfh) cells, a highly differentiated CD4 population, provide critical help for the development of antigen-specific B cell responses within the germinal center. Throughout the past decade, numerous studies have revealed the important role of Tfh cells in Human Immunodeficiency Virus (HIV) pathogenesis as well as in the development of neutralizing antibodies post-infection and post-vaccination… CONTINUE READING

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