Lymnaea epidermal growth factor promotes axonal regeneration in CNS organ culture.

@article{Wildering2001LymnaeaEG,
  title={Lymnaea epidermal growth factor promotes axonal regeneration in CNS organ culture.},
  author={Willem C Wildering and Petra M. Hermann and Andrew Bulloch},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2001},
  volume={21 23},
  pages={
          9345-54
        }
}
Members of the epidermal growth factor (EGF) family are frequently implicated in the injury response of the mammalian nervous system. Although this implication is supported by extensive molecular evidence, it is not underpinned by conclusive functional data. Recently, we found that expression of an EGF homolog from the pond snail Lymnaea stagnalis (L-EGF) is upregulated after axotomy in the adult CNS, suggesting a role for this molecule in the injury response of the CNS. In the present study we… CONTINUE READING

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