Lyme borreliosis vaccination: the facts, the challenge, the future.

@article{Schuijt2011LymeBV,
  title={Lyme borreliosis vaccination: the facts, the challenge, the future.},
  author={Tim J. Schuijt and Joppe W. R. Hovius and Tom van der Poll and Alje P. van Dam and Erol Fikrig},
  journal={Trends in parasitology},
  year={2011},
  volume={27 1},
  pages={40-7}
}
Lyme disease, or Lyme borreliosis, the most prevalent arthropod-borne disease in the Western world, is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato group and is predominantly transmitted through Ixodes ticks. There is currently no vaccine available to prevent Lyme borreliosis in humans. Borrelia outer membrane proteins are reviewed which have been investigated as vaccine candidates. In addition, several tick proteins are discussed, on which anti-tick vaccines have been… CONTINUE READING