Lyme borreliosis

@article{Stanek2012LymeB,
  title={Lyme borreliosis},
  author={Gerold Stanek and Gary P. Wormser and Jeremy S. Gray and Franc Strle},
  journal={The Lancet},
  year={2012},
  volume={379},
  pages={461-473}
}
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Genotyping of borrelia strains is of great importance for epidemiological, clinical, and evolutionary studies and many of them were implemented more or less successfully for diagnostic purposes.

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A condensed digest of the history of vaccine development up to new promising vaccine candidates and strategies that are targeted against Lyme borreliosis, including elements of the tick vector, the reservoir hosts, and the Borrelia pathogen itself are provided.

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A case of progressive mental deterioration in an older, immunocompromised patient is reported, and even though Koch's postulates were not met, it is likely that B. miyamotoi is an underrecognized cause of disease, especially in sites where Lyme disease is endemic.

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Despite improvements in prevention, diagnosis and treatment, Lyme borreliosis (LB) is still the most common arthropod-borne disease in temperate regions of the northern hemisphere, with risk of…

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