Lyme borreliosis — Problems of serological diagnosis

@article{Hofmann1996LymeB,
  title={Lyme borreliosis — Problems of serological diagnosis},
  author={PD Dr. med. H. Hofmann},
  journal={Infection},
  year={1996},
  volume={24},
  pages={470-472}
}
As long as test procedures are not standardized, the serological results of IgM-and IgG-antibodies in Lyme borreliosis must be interpreted with caution and always in the context of clinical signs and symptoms. False negative results occur primarily during the first weeks of infection. In erythema migrans of less than 4 weeks' duration, 50% of patients are seronegative even with newly designed ELISAs. At this early stage of the infection the therapeutic decision has to be established on the… CONTINUE READING
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