Lyme Disease in Pregnancy: Case Report and Review of the Literature

@article{Walsh2007LymeDI,
  title={Lyme Disease in Pregnancy: Case Report and Review of the Literature},
  author={Colin A Walsh and Elizabeth W. Mayer and Laxmi Baxi},
  journal={Obstetrical \& Gynecological Survey},
  year={2007},
  volume={62},
  pages={41-50}
}
Lyme disease is the most common vector-borne disease in the United States. A number of other spirochetal diseases, if contracted in pregnancy, have been shown to cause fetal harm and there is concern over a similar effect with gestational borreliosis. Previously published individual case reports have suggested a possible association between gestational borreliosis and adverse pregnancy outcome; however, no specific pattern of teratogenicity has been shown, and a causal relationship has never… 

Case Report: Lyme Borreliosis and Pregnancy - Our Experience

TLDR
A case series is reported of 11 pregnant women, 6 of which developed erythema migrans during pregnancy, 3 had myoarticular or neurological symptoms and 2 had positive serology, but did not develop any clinical symptoms, which stress on the importance of early antibiotic treatment in seropositive gestating women without symptoms.

A systematic review on the impact of gestational Lyme disease in humans on the fetus and newborn

TLDR
There was inconsistent evidence for adverse birth outcomes of Gestational LD in the epidemiological research, and uncommon adverse outcomes for the fetus may occur as a consequence of gestational LD.

A Case Report of Human Granulocytic Anaplasmosis (Ehrlichiosis) in Pregnancy and a Literature Review of Tick-Borne Diseases in the United States During Pregnancy

TLDR
After the completing the CME activity, physicians should be better able to diagnose tick-born diseases, implement best treatment options during the pregnancy, and assess the neonatal outcomes.

Lyme disease: clinical diagnosis and treatment.

TLDR
Clinicians need to be aware of the signs and symptoms of Lyme disease and knowing the regions where Borrelia infection is endemic in North America is important for recognizing patients at risk and informing the need for treatment.

Lyme disease in the United Kingdom

TLDR
New developments include diagnostic tests able to detect Lyme disease at an earlier stage, shorter durations of antibiotic therapy and potential advances in vaccines against Borrelia.

Borreliosis’ incidence among selected professionals in Poland

TLDR
The risk of contracting the Lyme disease among selected professionals in Poland is presented, especially in respect to forest workers, perceived as the highest risk group, by correlating data from many years of disease reports.

Pregnancy and Lyme disease

A literature review of individuals living with or contracting Lyme disease during pregnancy does not support an association with congenital anomalies or adverse pregnancy outcomes provided the

Arthropod-Borne Bacterial Diseases in Pregnancy

TLDR
Presentation, diagnosis, and treatment of the most common of these arthropod-borne bacterial diseases, including Lyme disease, Rocky Mountain spotted fever, tick-borne relapsing fever, typhus, plague, cat-scratch disease, and Carrión disease are discussed.

Lyme disease: Part I. Advances and perspectives.

Therapy of Lyme Disease

TLDR
The post-exposure prophylaxis, the main treatment-related phenomenon, the Jarisch-Herxheimer reaction, and the treatment modalities for special categories of patients, namely pregnant women, subjects suffering from post-treatment Lyme disease syndrome, possible Borrelia-associated skin manifestations, coinfections and Baggio-Yoshinary syndrome are discussed.

References

SHOWING 1-10 OF 44 REFERENCES

Teratogen update: Lyme disease.

TLDR
Gestational Lyme disease appears to be associated with a low risk of adverse pregnancy outcome, particularly with appropriated antibiotic therapy, and suggestions for management of clinical situations are presented.

Lyme disease and pregnancy outcome: a prospective study of two thousand prenatal patients.

Childhood neurologic disorders and Lyme disease during pregnancy.

Maternal Lyme disease and congenital malformations: a cord blood serosurvey in endemic and control areas.

TLDR
Within the endemic cohort, there were no differences in the rate of major or minor malformations or mean birthweight by category of possible maternal exposure to Lyme disease or cord blood serology, and the disparity between observations at the population and individual levels requires further investigation.

Gestational Lyme borreliosis. Implications for the fetus.

  • A. Macdonald
  • Medicine
    Rheumatic diseases clinics of North America
  • 1989
TLDR
It is my expectation that the spectrum of gestational Lyme borreliosis will expand into many of the clinical domains of prenatal syphilis, as well as investigate possible teratogenic effects that might occur if the spirochete reaches the fetus during the period of organogenesis.

Diagnosis of lyme disease.

The use of serologic testing and its value in the diagnosis of Lyme disease remain confusing and controversial for physicians, especially concerning persons who are at low risk for the disease. The

Maternal Lyme disease and congenital heart disease: A case-control study in an endemic area.

Treatment of erythema migrans in pregnancy.

TLDR
The course of the illness and the outcome of pregnancy were investigated in a prospective study of 58 consecutively enrolled pregnant women with typical erythema migrans and for at least some such cases a reasonable explanation (not associated with Lyme borreliosis) was found.

Facial Paralysis from Lyme Disease

  • R. DobieV. G. Caruso
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 1985
TLDR
This single case does not resolve the matter, since the ponenrs vestibular problem could have arisen from Infection or even spontaneously, but it would seem wise to avoid long-term use of amlnoglycoslde drops through a dry perforation, as used In the reported case.

Infants born to mothers with antibodies againstBorrelia burgdorferi at delivery

A serological survey over a 1-year period of 1416 mothers at delivery and their 1434 offspring for the presence of anti-Borrelia burgdorferi antibodies revealed a prevalence of 0.85%. Clinically