Lycopene inhibits proinflammatory cytokine and chemokine expression in adipose tissue.

@article{Gouranton2011LycopeneIP,
  title={Lycopene inhibits proinflammatory cytokine and chemokine expression in adipose tissue.},
  author={Erwan Gouranton and Cl{\'e}mentine Thabuis and C{\'e}line Riollet and Christiane Malezet-Desmoulins and Claire M El Yazidi and Marie Jos{\`e}phe Amiot and Patrick Borel and Jean François Landrier},
  journal={The Journal of nutritional biochemistry},
  year={2011},
  volume={22 7},
  pages={642-8}
}
Obesity is associated with a low-grade inflammation which is correlated with an increased secretion of pro-inflammatory cytokines and chemokines by adipose tissue, suspected to contribute to the development of insulin resistance. Because lycopene is mostly stored in adipose tissue and possesses anti-inflammatory properties, we hypothesize that lycopene could reduce the production of proinflammatory markers in adipose tissue. In agreement with this hypothesis, we observed a decrease of… CONTINUE READING

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