Lycopene inhibits disease progression in patients with benign prostate hyperplasia.

  title={Lycopene inhibits disease progression in patients with benign prostate hyperplasia.},
  author={S. Schwarz and U. Obermueller-Jevic and E. Hellmis and W. Koch and G. Jacobi and H. Biesalski},
  journal={The Journal of nutrition},
  volume={138 1},
Lycopene is a promising nutritional component for chemoprevention of prostate cancer (PCa). A possibly beneficial role of lycopene in patients diagnosed with benign prostate hyperplasia (BPH), who are at increased risk of developing PCa, has been suggested, although clinical data are lacking. Therefore, this pilot study aimed to investigate the effects of lycopene supplementation in elderly men diagnosed with BPH. A total of 40 patients with histologically proven BPH free of PCa were randomized… Expand
128 Citations

Paper Mentions

Interventional Clinical Trial
The purpose of this study is to assess the efficacy and safety of the Cardio formulation in reducing oxidized LDL [(Ox LDL (low density lipoprotein)] in overweight to mildly obese… Expand
ConditionsOxidized Low Density Lipoprotein
InterventionDietary Supplement
Interventional Clinical Trial
The purpose of this study is to assess the efficacy of a Prostate Health formulation on scores attained from the I-PSS questionnaire. Safety and tolerability of the formulation will… Expand
ConditionsProstate Health
InterventionDietary Supplement
Lycopene for the prevention and treatment of prostate disease.
  • D. Ilic
  • Medicine
  • Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
  • 2014
  • 9
Does Oral Lycopene Reduce Benign Prostate Enlargement/Hyperplasia(BPE/BPH)?
  • 1
  • PDF
Potential inhibitory effect of lycopene on prostate cancer.
  • 4
A Phase II Randomized Trial of Lycopene-Rich Tomato Extract Among Men with High-Grade Prostatic Intraepithelial Neoplasia
  • 25
  • Highly Influenced
Lycopene for the prevention of prostate cancer.
  • 95
Lycopene, Tomato Products, and Prostate Cancer Incidence: A Review and Reassessment in the PSA Screening Era
  • 77
  • PDF
Chemoprevention of prostate cancer with nutrients and supplements
  • 40
  • PDF
Lycopene Effects Contributing to Prostate Health
  • K. Wertz
  • Medicine
  • Nutrition and cancer
  • 2009
  • 43


Role of lycopene and tomato products in prostate health.
  • 111
  • PDF
Lycopene reduced gene expression of steroid targets and inflammatory markers in normal rat prostate
  • A. Herzog, U. Siler, +6 authors K. Wertz
  • Biology, Medicine
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2005
  • 127
Effects of Tomato Sauce Consumption on Apoptotic Cell Death in Prostate Benign Hyperplasia and Carcinoma
  • 100
Lycopene inhibits the growth of normal human prostate epithelial cells in vitro.
  • 125
  • PDF
Effect of Doxazosin on Oxidative Stress-Related Proteins in Benign Prostatic Hyperplasia
  • 9
BPH: epidemiology and comorbidities.
  • K. McVary
  • Medicine
  • The American journal of managed care
  • 2006
  • 305
Role of diet in prostate cancer development and progression.
  • 367
  • PDF
Synthetic and tomato-based lycopene have identical bioavailability in humans
  • 61