Lycopene bioavailability and metabolism in humans: an accelerator mass spectrometry study.

@article{Ross2011LycopeneBA,
  title={Lycopene bioavailability and metabolism in humans: an accelerator mass spectrometry study.},
  author={Alastair B Ross and Le Thuy Vuong and Jon L. Ruckle and Hans Arno Synal and Tim Schulze-K{\"o}nig and Karin Wertz and Robert Ruembeli and Rosa G Liberman and Paul L. Skipper and Steven R Tannenbaum and Alexandre Bourgeois and Philippe Alexandre Guy and Marc Enslen and Inge Lise Finn{\'e} Nielsen and Sunil Kochhar and Myriam Richelle and Laurent Bernard Fay and Gary Williamson},
  journal={The American journal of clinical nutrition},
  year={2011},
  volume={93 6},
  pages={1263-73}
}
BACKGROUND To our knowledge, there is no direct information on lycopene metabolism in humans. OBJECTIVE The objective of this study was to quantify the long-term human bioavailability of lycopene in plasma and skin after a single dose of (14)C-lycopene and to profile the metabolites formed. DESIGN We preselected 2 male subjects as lycopene absorbers and gave them an oral dose of 10 mg synthetic lycopene combined with ≈6 μg [6,6',7,7'-(14)C]lycopene (≈30,000 Bq; 92% trans lycopene). The… CONTINUE READING