Lyase-catalyzed degradation of alginate in the gelled state: effect of gelling ions and lyase specificity.

Lyase-catalyzed degradation has been proposed as a more cell-friendly alternative to dissolution of alginate gels than using chelating agents. In this study, we investigated the effect of lyase specificity on degradation of alginate gels, including the effect of crosslinking ions with different affinity for the polymer. Degradation kinetics and products… CONTINUE READING