LuxS-mediated signaling in Streptococcus mutans is involved in regulation of acid and oxidative stress tolerance and biofilm formation.

@article{Wen2004LuxSmediatedSI,
  title={LuxS-mediated signaling in Streptococcus mutans is involved in regulation of acid and oxidative stress tolerance and biofilm formation.},
  author={Zezhang T Wen and Robert A Burne},
  journal={Journal of bacteriology},
  year={2004},
  volume={186 9},
  pages={2682-91}
}
LuxS-mediated quorum sensing has recently been shown to regulate important physiologic functions and virulence in a variety of bacteria. In this study, the role of luxS of Streptococcus mutans in the regulation of traits crucial to pathogenesis was investigated. Reporter gene fusions showed that inactivation of luxS resulted in a down-regulation of… CONTINUE READING