Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3.

@article{Yang2014LuteolinEP,
  title={Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3.},
  author={M Yang and Chau-Jong Wang and Nai-Fang Chen and Wen-Hsin Ho and Fung-Jou Lu and T. M. Tseng},
  journal={Chemico-biological interactions},
  year={2014},
  volume={213},
  pages={60-8}
}
The potential use of low-dose chemotherapy has been appealing because lower dosages are more attainable during cancer therapy and cause less toxicity in patients. Combination therapy of paclitaxel, a promising frontline chemotherapy agent, with natural anti-tumor agents that are considerably less toxic and possess the capability of activating additional apoptotic signals may provide a rational molecular basis for novel chemotherapeutic strategies. Luteolin, a natural flavone, possesses multiple… CONTINUE READING

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Luteolin

Y. Lin, R. Shi, X. Wang, H. M. Shen
a flavonoid with potentials for cancer prevention and therapy, Curr. Cancer Drug Targets 8 • 2008
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