Luteolin Isolated from the Flowers of Lonicera japonica Suppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells

@inproceedings{Kang2010LuteolinIF,
  title={Luteolin Isolated from the Flowers of Lonicera japonica Suppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells},
  author={Ok-Hwa Kang and Jang-gi Choi and John-hwa Lee and Dong-Yeul Kwon},
  booktitle={Molecules},
  year={2010}
}
  • Ok-Hwa Kang, Jang-gi Choi, +1 author Dong-Yeul Kwon
  • Published in Molecules 2010
  • Chemistry, Medicine
  • Luteolin (3',4',5,7-tetrahydroxylflavone) is a plant flavonoid and pharmacologically active agent that has been isolated from several plant species. In the present study, the effect of luteolin from the flowers of Lonicera japonica on phorbol 12-myristate 13-acetate (PMA) plus A23187-induced mast cell activation was examined. Luteolin significantly inhibited the induction of inflammatory cytokines such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-8, IL-6 and granulocyte-macrophage… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 32 REFERENCES

    P38-associated pathway involvement in apoptosis induced by photodynamic therapy with Lonicera japonica in human lung squamous carcinoma CH27 cells.

    • Henry W-C Leung, M-J Hour, +4 authors H. S. Lee
    • Chemistry, Medicine
    • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
    • 2008
    VIEW 1 EXCERPT