Luteolin Inhibits Behavioral Sensitization by Blocking Methamphetamine-Induced MAPK Pathway Activation in the Caudate Putamen in Mice

@inproceedings{Yan2014LuteolinIB,
  title={Luteolin Inhibits Behavioral Sensitization by Blocking Methamphetamine-Induced MAPK Pathway Activation in the Caudate Putamen in Mice},
  author={Tinglin Yan and Lu Li and Baiyu Sun and Fei Liu and Peng Yang and Teng Chen and Tao Li and Xinshe Liu},
  booktitle={PloS one},
  year={2014}
}
GOAL To investigate the effect of luteolin on methamphetamine (MA)-induced behavioral sensitization and mitogen-activated protein kinase (MAPK) signal transduction pathway activation in mice. METHODS Mice received a single dose of MA to induce hyperactivity or repeated intermittent intraperitoneal injections of MA to establish an MA-induced behavioral sensitization mouse model. The effect of luteolin on the development and expression of MA-induced hyperactivity and behavioral sensitization… CONTINUE READING
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