Luteolin Attenuates Airway Mucus Overproduction via Inhibition of the GABAergic System

@inproceedings{Shen2016LuteolinAA,
  title={Luteolin Attenuates Airway Mucus Overproduction via Inhibition of the GABAergic System},
  author={Mei-Lin Shen and Chen-Hung Wang and Ching-Huei Lin and Ning Zhou and S. L. Kao and Dong Chuan Wu},
  booktitle={Scientific reports},
  year={2016}
}
Airway mucus overproduction is one of the most common symptoms of asthma that causes severe clinical outcomes in patients. Despite the effectiveness of general asthma therapies, specific treatments that prevent mucus overproduction in asthma patients remain lacking. Recent studies have found that activation of GABAA receptors (GABAAR) is important for promoting mucus oversecretion in lung airway epithelia. Here, we report that luteolin, a natural flavonoid compound, suppresses mucus… CONTINUE READING
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